Curriculum Vitae


(see also Who's who in France,  America, and Who's who in the World, Who’s Who in Medicine, Science and Technology)


ROBERT Ladislas (Leslie , Laszlo)


Born in Budapest (Hungary), 1924




                Faculties of Sciences and Medicine, Szeged, Targu-Mures (Transylvania), Budapest and Paris


                M.D., University of Paris: " Action de la température sur les réactions biologiques". Silver Medal


                Ph.D., Lille, France :" L'élastine et les élastases".


                Scientific carrier:  tenured Member of the French National Research Center (CNRS) since 1950.


                Research Director (class 1) since 1974


                retired from CNRS, September 1994


                1995-1997: Director of the Connective Tissue Research Team in the Department of Cell Biology, Sciences Faculty, University  Paris 7.


                Since 1998: Laboratoire de Recherche Ophtalmologique, Faculté de Médecine -Hôtel Dieu, Université Paris 5.




                Undergraduate courses (Masters Degree) in Aging Biology


                Graduate courses in Connective Tissue Biochemistry and Aging Biology


                Degree of Specialization in Geriatrics - courses in basic Gerontology at several Medical Schools


                Director and Supervisor of about 50 Ph.D. Theses


                Worked in the following Laboratories


                Institute of Biochemistry, Faculty of Medicine, Budapest, Profs R.B.STRAUB and  I. BACH. 1945-1948


                Department of Biochemistry, Faculty of Medicine, Paris, Prof. M. POLONOVSKI, Prof. M-F. JAYLE. 1949-1959


                Department of Biochemistry, Illinois University School of Medicine, Chicago, USA, Prof. R.J. WINZLER. 1959-1960


                Department of Biochemistry, College of Physicians and Surgeons, Columbia University, New-York, USA, Prof. Z. DISCHE. 1960-1961


                Institute of Immunology, Hôpital Broussais, Prof. B.N. HALPERN.1962-1966


                Founder of the French Laboratory of Connective Tissue  Biochemistry, then  Research Laboratory of the CNRS. 1966-1994, at the Henri Mondor Hospital Medical School, University Paris XII.




                Laureate of the Medical School, Paris, 1953


                Prize of the Association of Scientific Journal Editors, 1962


                Reiss Prize  of Ophthalmology ( with  Prof. Y. POULIQUEN), 1970


                Honorary Doctor Degree of the Semmelweis University, Budapest, Hungary, 1991


                Verzar Medal for Gerontological Research, University of Vienna (Austria), 1994


                Member of the Hungarian Academy of Sciences, 1995


Elected corresponding Member of the Scientific Academy of Westfalian-Northern Rhenany (Germany), 1996


                NOVARTIS Prize, International Society of Gerontology, 1997


                Scientist of the year, French Society of antioxidants, 2008


Member of French and Foreign Societies :


                               Société de Chimie Biologique et de Biologie Moléculaire, France


                               Biochemical Society, UK


                               American Chemical Society, USA


                               New York Academy of Sciences, USA


                               Member of the Scientific Board of the Research Institute on Arteriosclerosis, University of Münster, Germany, 1972-1996


                               Founder, General Secretary, President and since 1986, Honorary President of the French Society of Connective Tissue Research


                               Founder of the Federation of European Connective Tissue Societies                                                   President  of the French Atherosclerosis Society


Member of the Editorial Board of the following reviews


                               Journal of Bology






                               Archives of Gerontology and Geriatrics


                               Clinical Physiology and Biochemistry






Scientific contributions




                               Mécanismes Cellulaires et Moléculaires du Vieillissement, Masson, Paris, 1983


                               Les Horloges Biologiques, 1989, Flammarion, Paris


                               Le vieillissement, de l'Homme aux cellules, 1994, Belin-CNRS


                               Le Vieillissement, Faits et Théories, 1995, Dominos-Flammarion, Paris


                               Vieillissement du cerveau et démences, 1998, Nouvelle Bibliothèque Scientifique, Flammarion, 2ND ED : 2003


                               Les Temps de la Vie, 2002, Nouvelle Bibliothèque Scientifique, Flammarion.


                               Bio-Logiques du vieilissement (With PA Miquel), 2004, Kimé , Paris


                               Les secrets de la longévité, 2006, Editions Louis Audibert, Paris


                Series Editor: "Frontiers of Matrix Biology", Karger, Bâle, 11 Volumes


                               Co-Editor (with A.M. Robert): Colloque International n° 287 du CNRS:"Biochimie Normale et Pathologique du Tissu Conjonctif", 2 volumes, 1980


                               Co-Editor (with F. DELBARRE et H.KAISER) of "Les maladies du Tissu Conjonctif", 1980 and (with F. DELBARRE et H. GREILING) of" Pharmacologie cellulaire et moléculaire des maladies du Tissu Conjonctif", 1981, Colloques Franco-Allemands de Rhumatologie, Boerhinger-Ingelheim, France


                                Co-Editor "Elastin and Elastases", 2 volumes, 1989 CRC Press, Boca Raton, Florida


                               Editor : Molecular Biology and Pathology of Elastin, (Ciba Foundation symposium), 1995, Wiley, London


Publications  in International Scientific Journals


                More than 1000


List of publications since 2002.


Cell-matrix interactions in cancer spreading - effect of aging;. An introduction.


Robert L


In Seminars in Cancer Biol. Robert L. (Guest Ed). 2002, 12: 157-16


Fibronectin in malignancy. Effect of Aging.




Seminars in Cancer Biol. 2002,12 :187-195


Les Temps de la Vie.


Robert L.


 Flammarion, Paris, 2002


Regulation of elastase-type endopeptidase activity, MMP-2 and MMP-9 expression and activation in human dermal fibroblasts by fucose and a fucose-rich polysaccharide.


Isnard N, Péterszegi G, Robert AM, Robert L


Biomed. Pharmacother. 2002,  56: 258-264


 Protection de la cornée contre l'effet des protéases. Etude expérimentale d'oligomères procyanidoliques (OPC) sur la cornée bovine.


Robert AM, Robert L, Renard G


J Fr. Ophtalmol. 2002,205: 351-355


Inhibition of cell proliferation and fibronectin biosynthesis by Na ascorbate.


Péterszegi G, Dagonet F, Labat-Robert J, Robert L


 Eur. J. Clin. Invest . 2002, 32: 372-380


Serum elastase activity, serum elastase inhibitors, and occurrence of carotid atherosclerotic plaques.


Zureik M, Robert L, Courbon D, Touboul PJ, Bizbiz L, Ducimetière


Circulation. 2002,105: 2638-2645


 Effect of hyaluronan on matrix metalloproteinase expression in fibroblasts and keratocytes.


Isnard N, Legeais JM, Renard G, Robert L.


In:  Kennedy JF, Phillips GO, Williams PA Eds. Hyaluronan. Woodhead Pub. Ltd. Vol 1, 2002, pp 531- 535          


 Aging and  regulation of hyaluronan biosynthesis, comparatives studies on human skin fibroblasts and corneal keratocytes.


                ,Robert L, Fodil I, Isnard N, dupuy F, Robert AM, Renard G.


                In:  Kennedy JF, Phillips GO, Williams PA Eds. Hyaluronan. Woodhead Pub. Ltd. Vol 1, 2002,pp 537- 543           


Mécanismes et mesure du vieillissement.


Robert L.


La lettre du Biologiste. 2002, p 2


 Elastin, past, present and future.


Robert L.


Pathol. Biol. 2002, 50: 503-511


Modulation of cell-phenotype during in vitro aging. Glycosaminoglycan biosynthesis by skin fibroblasts and corneal keratocytes.


Isnard N, Fodil I, Robert L, Renard G


Exp. Gerontol. 2002, 37: 1377-1385


Cell-elastin interactions :essential results of the first years of research on the elastin-receptor.


Robert L., Fülöp T.


In :Tamburro AM, Pepe A. Eds. Elastin 2002, EditricHermes . pp139-158


Le vieillissement du cerveau.


Robert L.


 Champs-Flammarion, Paris 2003


The mechanisms of aging : from genetic to epigenetic.


Robert L., Labat-Robert J. 


Presse Médicale .2003,32 :609-618


Effect of sulfated GAGs on the expression and activation of MMP-2 and MMP-9 in corneal and dermal explant cultures.


Isnard N, Robert L, Renard G.


 Cell Biol. Int  2003,27 :779-784


Aging- from basic research, clinical gerontology and « anti-aging » medicine. Robert L


Biomed Pharmacother, 2003,57 :541-542


Aging from basic research to pathological applications.


Robert L, Robert AM.


 Pathol Biol. 2003,51 :543-549


Pharmacological properties of fucose. Applications in age-related modifications of connective tissues.


Péterszegi G., Fodil-Bourahla I., Robert AM., Robert L. 


Biomed Pharmacother . 2003,57 :240-245


The age-dependent vasodilation and endothelial calcium influx induced by elastin peptides are modulated by extracellular glucose level.


Faury G, Robert L, Verdetti J.


Biomed Pharmacother. 2003, 57 :216-222


Effect of L-fucose and fucose-rich oligo- and polysaccharides (FROP-s) on skin aging : penetration, skin tissue production and fibrillogenesis.


Fodil-Bourahla I, Bizbiz L, Schoevaert D., Robert AM, Robert L.


 Biomed Pharmacother. 2003, 27 :209-215


Studies on skin aging. Preparation and properties of fucose-rich oligo-and polysaccharides. Effect on fibroblast proliferation and survival.


Péterszegi G, Isnard N, Robert AM, Robert L.


 Biomed Pharmacother. 2003,57 :187-194


Protection by L-Fucose and fucose-rich polysaccharides against ROS-produced cell death in presence of ascorbate.


Péterszegi G, Robert AM, Robert L.


Biomed Pharmacother. 2003,57 :130-133


Sites cryptiques et matrikines :effects cellulaires des peptides de fibronectine et de laminine.


Labat-Robert J.


 J. Soc. Biol. 2003,197 : 45-51


Le vieillissement entre recherche fondamentale, geriatrie clinique et medecine anti-age.


Robert L 


Pathol. Biol. 2003, 51 :541-542


Age-dependent remodeling of connective tissue :role of fibronectin and laminin.


Labat-Robert J


 Pathol. Biol. 2003, 51 :563-568


Effect of a fucose-rich polysaccharide preparation on the age-dependent evolution of the skin surface micro-relief.


Robert C., Robert AM, Robert L


Pathol Biol. 2003,51 :586-590


 Le » pouvoir « montant des « jeunes vieux ». Rôle de la science.




In : Pouvoir et Vie. Actes de L’Université Européenne de Nice, Juillet 2003, Miquel PA &  Mihali C. Eds. Pp 231-234


.Cell-matrix interactions in aging : role of receptors and matricryptins.


Labat-Robert J.


Ageing. Res. Rev. 2004, 3 : 233-247


Effect of L-Fucose and fucose-rich polysaccharides on elastin biosynthesis, in vivo and in vitro.


L Robert, I. Fodil-Bouralha, L. Bizbiz, A.M. Robert


Biomed.Phamacotherapy. 2004, 58 : 123-128


Effects of L-Fucose and fucose-rich oligo- and polysaccharides (FROP-s) on collagen biosynthesis by human skin fibroblasts. Modulation of the effect of retinol, ascorbate and -tocopherol.


                L. Robert, I. Fodil-Bouralha, L. Bizbiz, AM Robert


                Biomed. Pharmacotherapy . 2004, 58 :65-70


Pharmacology of skin aging. Stimulation of glycosaminoglycan biosynthesis by L-fucose and fucose-rich polysaccharides, effect of in vitro of fibroblasts.


       N. Isnard, L. Robert


       Biomed Pharmacotherapy. 2004, 58 :202-204


The elastin-laminin receptor-mediated matrix degradation. Effect of glucose concentration. Role in atherosclerosis.


Faury G., J. Verdetti., Fülöp T, Robert L.


In : Intern Congress Series 1232 : Atherosclerosis XIII. pp 411-413, 2004


Anti-aging medicine: The History.  The three avenues of gerontology: from basic research to clinical gerontology and anti-aging medicine. Another French paradox.


L .Robert


J Gerontol . Biol Sci .  2004, 59 A,(6) : 540-542.   


Mécanismes et mesure du vieillissement.


L. Robert


      Immuno-analyse & Biologie Spécialisée (IMMBIO). 2004, 19 : 215-218


Effect of a preparation containing a fucose-rich polysaccharide on periorbital wrinkles of human voluntaries.


C.Robert, A.M. Robert, L. Robert.


Skin. Res. Technol. 2004, 10 :16


Le « pouvoir » montant des « jeunes vieux ». Rôle de la science.


L. Robert


In : Miquel PA, Mihali C.. Eds. Pouvoir et vie. Actes de l’université européenne d’été de Nice. Pp 231-234. Idea Design & Print, Klug-Napoca, 2004


Mécanismes épigénétiques post-transcriptionnels des régulations des fonctions physiologiques et de leur déclin au cours du vieillissement


L. Robert


J. Soc. Biol. 2004,198 :257-262


Trente ans de fibronectine , rôle dans la transformation maligne et dans le vieillissement


J. Labat-Robert


J. Soc Biol. 2004,198 :287-291


Matrix remodeling and atherosclerosis. Effect of age.


L.  Robert


In : Razzaque MS Ed. Fibrogenesis, cellular and molecular basis. Landes Bioscience/, Georgetown and Kluwer Academic/Plenum Pub,NY, chapter  9, pp 104-117 , 2004


Negative regulation of corneal elastin biosynthesis


N. Isnard, L. Robert, G. Renard.


Matrix biology, 2004, 23 :410


Mécanismes fondamentaux impliqués dans le vieillissement cellulaire et tissulaire


L. Robert


In : MM. Denis et Veyssier (Eds) "Vieillissement : les données biologiques". Elsevier, Chapitre 2,


Longévité et déclin, mécanismes génétiques etépigénétiques.


L. Robert


BioFutur, 2005,253 :33-37


Les maladies liées à l’âge.


L. Robert


BioFutur, 2005,253 :39-44


The Extracellular Matrix During Normal Development and Neoplastic Growth.


J. Labat-Robert, L. Robert


In : Progress in Molecular and Subcellular Biology. Macieira-Coelho A Ed.  Development Biology of Neoplastic Growth. Springer Verlag Berlin-Heidelberg, 2005


Pp 79-106


Presence and active synthesis of the 67 kDa elastin-receptor in human circulating white blood cells


A  Larbi,  G  Levesque, L  Robert, D  Gagné,  N  Douziech, T. Fülöp Jr


Biochem Biophys Res Comm, 2005,352 :787-792


Mécanismes épigénétiques dans le vieillissement. (Mise au point)


L.  Robert


Alzheimer Actualités (Fondation IPSEN), 2005,180 :8-11


 L. Robert


Proteases et Vieillissement


In : Eléments de prévention du vieillissement pathologique  Collection «            Abrégés de Médecine » ,pp 13-35, 2005, Masson-Elsevier


MMP-type endopeptidase activity in the cornea. Its evolution during organ culture storage at the Eye Bank. Effect of hyaluronan.


N. Isnard, P. Sabatier, A.M. Robert, L. Robert, G. Renard


Pathol. Biol. 2005, 53, 424-429


Cell-elastin interaction and signaling.


L.  Robert


Pathol. Biol. 2005, 53, 399-404


Effect of procyanidolic oligomers of Vitis vinifera on the biosynthesis and excretion of corneal glycosaminoglycans.


A.M. Robert, L. Robert, G. Renard


Pathol. Biol. 2005, 53, 411-415


  Introduction : matrix biology in the 21st century. From a static-rheological role to a dynamic-signaling function.


J. Labat-Robert, L. Robert


Pathol. Biol. 2005, 53, 369-371


Elastin peptides induced oxidation of LDL by phagocytic cells


T. Fülöp Jr, A. Larbi , A. Fortun, L. Robert, A. Khalil


¨Pathol. Biol. . 2005, 53, 416-423


Fritz Verzar’s contribution to Experimental Gerontology –An assessment after half a century


                L. Robert, I. Zs-Nagy


                Arch. Gerontol. Geriatr.


Effet d’un polysaccharide riche en fucose (FROP-3) sur le vieillissement cutané. Etude indentométrique sur volontaires humains.




C. Robert, AM Robert, L. Robert


J. Med. Esth. Et Chir. Derm, 2005, 32 :269-274


952.       Le Vieillssement : du cellulaire à la fonction. Préface.


L. Robert.


Cahiers de la FIAPA, n°4, Juin 2005, , pp IX-XI


Studies on corneal wound healing : effect of Fucose on iodine vapor burnt rabbit corneas.


Isnard N, Bourles-Dagonet, Robert L, Renard G.


Ophthalmologica  2005;219:324-333


Étude de l’effet des oligomères procyanidoliques sur la fibrillogénèse de la cornée


Robert AM, Robert L, Renard G.


J. Fr. ophtalmol. 2005, 28 : 1017-1025


Retard de cicatrisation – Sénescence.


L. Robert


In : Plaies et cicatrisations. Meaume S, Dzrzurz O, Téot L Eds. Pp 45-48, Masson Paris, 2005.


Effect of procyanidolic  oligomers  on corneal


 collagens of rabbits treated  by excimer laser photoablation.


Robert AM, Salvodelli M, Legeais JM, Robert L, Renard G.


Biomedicine & Pharmacol. 2006, 60 :113-120


 Effect of high glucose concentration  on corneal collagen biosynthesis


Robert L, Menasche M, Robert AM, Renard G.


Ophthalmologica  . 2006;220:317-22.


Fritz Verzar was born 120 years ago : His contribution to experimental  gerontology  through the collagen research as assessed after half a century


Robert L.


Arch. Gerontol. Geriatrics. 2006, 43 : 13-43


The metabolic syndrome and the Maillard reaction. An introduction.


Labat-Robert J, Robert L


Pathol Biol . 2006 ,  54 : :371-374.


An original approach to aging: an appreciation of Fritz Verzar's contribution in the light of the last 50 years of gerontological facts and thinking.


Robert L.


Gerontology. 2006; 52:268-74.


Pharmacological properties of rhamnose-rich polysaccharides, potential interest in age-dependent alterations of connectives tissues.


Andres E, Molinari J, Peterszegi G, Mariko B, Ruszova E, Velebny V, Faury G, Robert L.


Pathol Biol . 2006, 54: 420-5.


Effect of advanced glycation end-products on cell proliferation and cell death.


Peterszegi G, Molinari J, Ravelojaona V, Robert L.         


Pathol Biol . 2006, 54: 396-404


Protection by rhamnose-rich polysaccharides against the cytotoxicity of Maillard reaction products.


Ravelojaona V, Molinari J, Robert L.


Biomed Pharmacother. 2006, 60:359-62.


Conciliating science, philosophy and religion to better


understand aging: an interview with Dr. Ladislas Robert


Tamas Fulop


Biogerontology 2007, 8: 63–70


The Effect of Cell Matrix Interactions and Aging on the Malignant Process.


Labat-Robert J, Robert L, In Van de Woude, Klein G. Eds.


Adv. Cancer Res. 2007,  98 :  221-259


Bourges J-L, Robert AM, Robert L*, Renard G


Zonular fibers


Pathologie-Biologie, 2007, 55 :347-359


 Robert L


Le vieillissement, ses mécanismes et ses théories.


In :  Miquel PA. ed : Evolution des concepts fondateurs de la biologie du XXIe siècle.


DeBoeck, Belgique


Robert L.


120 Eve Született Verzar Frigyes, a kiserleti gerontologia megalapitoja : Visszatekintés EgFél ÉVSZAZADRA ;


Magyar Tudomany. 2007, 3 :320-331


                Péterszegi G, Robert AM, Robert L. Renard G.


Importance de la réaction de Maillard en ophtalmologie.


J. Soc.  Biol. 2007,  201 :209-214


Ravelojaona V, Péterszegi G, Molinari J, Gesztesi JL, Robert L


Démonstration de l’effet cytotoxique des produits avancés de la glycation (AGE-S)


J. Soc. Biol. 2007, 201 : 185-188


Robert A.M., Robert CS., Robert L.*


Symmetry breaking in biological systems. From molecules to tissues.


 Struct Chem ,2007, 18 :899-907


DOI 10.1007/s11224-007-9212-8


 V. Ravelojaona, L. Robert*,   A-M. Robert


Effect of cellular  aging on collagen biosynthesis.


II. Collagen synthesis and deposition by a human skin fibroblast strain


over 25 passages)


 Archiv. Gerontol. Geriatr. (2007), doi:10.1016/j.archger.2007.08.017


Archives of Gerontology and Geriatrics 47 (2008), pp. 368-376


G. Péterszegi, E. Andrès, J. Molinari, V. Ravelojaona, L. Robert*


Effect of cellular aging on collagen biosynthesis. I. Methodological considerations and pharmacological applications


Archiv. Gerontol. Geriatr. (2007), doi:10.1016/j.archger.2007.08.019


Archives of Gerontology and Geriatrics 47 (2008), pp. 356-367


Robert L.


Télomères et vieillissement. Rôle dans les maladies liées à l’âge


Revue de Gériatrie, 2007, 32 :645-651


Ravelojaona V., Robert A.M., Robert L, Renard G.


Collagen Biosynthesis in Cell Culture - Comparison of Corneal Keratocytes and Skin Fibroblasts. Effect of Rhamnose-Rich Oligo- and Polysaccharides


Pathologie Biologie (2007), doi:10.1016/j.patbio.2007.10.003


Pathologie-Biologie, 2007,56 :66-69






Biogerontology DOI:10.1007/s10522-007-9122-6


Biogerontology. 2008 Apr;9(2):119-133.


J. Molinari 1, E. Ruszova 2, V. Velebny 2, L. Robert 1 *


Effect of Advanced Glycation Endproducts on Gene Expression Profiles of human dermal fibroblasts..


BioGerontology. 2008,9 :177-182


BGEN-08-6 (2008), DOI : 10.1007/s10522-008-9129-7


 Labat-Robert J


La fibronectine plasmatique, marqueur nutritionnel


La Revue de Gériatrie, 2008, 33 :175-180


Robert L


Le vieillissement, ses mécanismes et ses théories.


In : Biologie du XXIe Siècle, Evolution des concepts fondateurs (PA.Miquel Ed) de Boeck, & Larcier sa, 2008, Bruxelles, pp 347-368


Faury G, Ruszova E., Molinari J. Mariko B, Raveaud S, Velebny V, Robert L


The -L–Rhamnose recognising lectin site of human dermal


fibroblasts functions as a signal transducer. Modulation of Ca2+


fluxes and gene expression.


BBA , 2008, 1780 :1388-1394




Robert L, Labat-Robert J, Robert AM


Physiology of skin aging. Physiologie du vieillissement cutané


Pathol-Biol. Ms. No. PATBIO-D-08-00150


 Robert L, Robert AM.


Immuno-Inflammatory Athero-Arteriosclerosis Induced by Elastin Peptides. Effect of Age.In : Fulöp T, Francesci C, Hirokawa K, Pawelec G. Eds. Handbook on Immunosenescence. pp 1089-1116. DOI 10.1007/978-1-4020-9062-2_1,Springer Science + Business Media B.V., 2009


.Ravelojaona V., Robert A.M., Robert L.




Arch. Gerontol. Geriatr  (2008), doi :10.1016/j.archger.2007.12.004


Arch. Gerontol. Geriatr. (2009), 48 :151-154


  Robert L, Robert AM.


Protéases et vieillissement. In :  Trivalle C. Ed. Gérontologie préventive. Elsevier-Masson SAS. Paris, 2009, pp 54-60


Robert L.


Introduction to the special issue of Pathologie-Biologie devoted to aging




Doi 10.1016/patbio.2009.09.005


 Robert L


The Maillard reaction, its nutritional and physiopathological aspects.




DOI 10.1016/patbio.2009.09.006


 Robert L*, Robert AM, Renard G.


Biological  Effects  of  Hyaluronan  in  Connective  Tissues, Eye, Skin, Venous Wall. Role in Aging. Effets biologiques de l’hyaluronane dans les tissus conjonctifs, l’œil, la peau, la paroi veineuse. Rôle dans le vieillissement.




DOI 10.1016/j.patbio.2009.09.010




Robert L.


The Maillard reaction. From nutritional Problems to Preventive Medicine.




DOI 10.1016/j.patbio.2009.09.004


Robert L


Elastine et fibres élastiques, vieillissement et pathologie. Une introduction


Médecine et longévité


DOI 10.1016/j.mlong.2009.10.007






Robert L.


Le vieillisement cutané. Rôle de l’élastine.


Médecine et Longévité.


DOI 10.1016/j.mlong.2009.10.009






L. Robert٭, J. Labat-Robert, A.M. Robert


            Receptors and aging: Dedicated to the memory of Paul Ehrlich


            for the 100th anniversary of his Nobel Prize


                Arch. Gerontol. Geriatr. 2010, 51: 260-263


                doi 10.1016/j.archger.2009.11.013


Robert L.


The Saga of κ-elastin, or the Promotion of Elastin Degradation Products from “garbage” to Receptor Agonists and Pharmacologically Active Principles.


Conn. Tissue. Res. 2010. 51 : 8-13


DOI: 10.1080/03008200902855925


L.Robert, J.Labat-Robert, A.M.Robert


         Genetic, Epigenetic and Posttranslational  Mechanisms of Aging.*


           Biogerontology,2010, 11 :387-399


           DOI: 10.1007/s10522-010-9262-y


 L. Roberta,*, J. Molinarib, V. Ravelojaonaa, E. Andrèsb, A.M. Roberta


Age- and passage-dependent upregulation of fibroblast elastase-type endopeptidase activity.  Role of advanced glycation endproducts, inhibition by fucose- and rhamnose-rich oligosaccharides.


Archiv. Gerontol. Geriatr. 2010,50 :327-331


DOI :10.1016/j.archger.2009.05.006


 Robert L, Labat-Robert J, Robert AM.


Le vieillissement en pièces détachées et ses conséquences pour la médecine anti-âge.


J. Méd. Esth. Et Chir. Derm. 2010, 37 , 146 : 73-79


Robert L.


Introduction au numéro spécial consacré à la cytogérontologie et son rapport à la gériatrie.


Médecine et Longévité. 2010, 2 : 112-113


Doi :10.1016/j.mlong.2010.07.006


Robert L., Labat-Robert J., Robert AM.


Vieillissement cellulaire, télomères et maladies liées à l’âge


Médecine et Longévité, 2010, 2 : 151-161


Doi :10.1016/j.mlong.2010.07.005


Robert L., Mecham R.


Tribute to Toni Tamburro


Path Biol, 2010, 58 : 239-240


 Robert L.


Tribute to Torvard Laurent


Path. Biol., 2010, 58 : 241


G. Faury, J. Molinari, E. Rusova, B. Mariko, S. Raveaud,, P. Huber, V. Velebnyf, A.M. Robert and L. Robert


Receptors and aging: Structural selectivity of the rhamnose-receptor on Fibroblasts as shown by Ca2+-mobilization and gene expression profiles


Arch. Gerontol. Geriatr. 2011, 53 :106-112


DOI : 10.1016/j.archger.2010.05.017


Labat-Robert J, Robert L. Pouliquen Y.


Les tissus conjonctifs, de l’origine au concept à sa « mutation » en matrice extracellulaire. Application aux tissus oculaires. Contribution à l’histoire des Sciences Médicales.


Pathologie Biologie, 2011, 59 :183-186


DOI 10.1016/j.Patbio.2011.04.006


Robert L., Robert AM.., Labat-Robert J.


The Maillard Reaction – Illicite (Bio)chemistry in Tissues and Food.


Pathologie Biologie,2011,59(6) :321-328


DOI 10.1016/j.Patbio.2011.04.007


Robert L., Labat-Robert J., Robert AM.


       Physiology of skin aging


       Clin Plastic Surg. 2012, 39 :1-8


       Doi :10.1016/j.cps 2011.09.006


Robert L.


Longevity and Aging, Genetic and Postgenetic Mechanisms. Which Target to              Choose for Postponing and Treating Age-related Diseases.


        Eur. Geriatr. Medicine. 2012,3 : 61-66


      DOI : 10.1016/j.eurger.11.004




Robert L, Labat-Robert J, Robert AM.


Longévité et vieilissement. A l’occasion du 110ème anniversaire de la naissance de H. Rubinstein


        Journal Med Esth et Chir Derm. 2012, 39, 153 (mars) : 35-42


 Robert L., Labat-Robert J., Robert AM.


Aging of the Extracellular Matrix.


Médecine & Longévité. 2012,


DOI : 10.1016/j.mlong.2012.02.003


Borel JP, Maquart FX, Robert AM, Labat-Robert J, Robert L.


Celebration of t he 50th aniversary of the foundation of hhe French Society for Connective tisue Research. Its short history in the frame of the origin and the development of this discipline.


Pathologie Biologie. 2012,60 :2-6


DOI10.16/j.patbio ;2011.10.001


 Labat-Robert J.


Cell-Matrix Interactions, the role of fibronectin and integrins. A survey. Pathologie Biologie. 2012.60 : 15-19


DOI :10